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Thomas Schmelter Selected Research

sagopilone

6/2013Prospective, multicenter, randomized, independent-group, open-label phase II study to investigate the efficacy and safety of three regimens with two doses of sagopilone as second-line therapy in patients with stage IIIB or IV non-small-cell lung cancer.
1/2013A double-blind, randomized phase II study to evaluate the safety and efficacy of acetyl-L-carnitine in the prevention of sagopilone-induced peripheral neuropathy.
10/2010Phase II study evaluating the efficacy and safety of sagopilone (ZK-EPO) in patients with metastatic breast cancer that has progressed following chemotherapy.

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Thomas Schmelter Research Topics

Disease

10Macular Edema
01/2022 - 08/2012
3Macular Degeneration (Age-Related Maculopathy)
09/2021 - 01/2019
3Diabetic Retinopathy (Retinopathy, Diabetic)
01/2019 - 08/2012
3Neoplasms (Cancer)
12/2015 - 10/2010
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2015 - 06/2013
2Ovarian Neoplasms (Ovarian Cancer)
01/2013 - 10/2010
1Polypoidal Choroidal Vasculopathy
05/2021
1Retinal Vein Occlusion
01/2021
1Choroidal Neovascularization
01/2019
1Diarrhea
12/2015
1Exanthema (Rash)
12/2015
1Fatigue
12/2015
1Ovarian Cysts (Ovarian Cyst)
05/2015
1Metrorrhagia (Spotting)
05/2013
1Hemorrhage
05/2013
1Peripheral Nervous System Diseases (PNS Diseases)
01/2013
1Prostatic Neoplasms (Prostate Cancer)
01/2013
1Hyperemia
08/2012
1Pain (Aches)
08/2012
1Hypertension (High Blood Pressure)
08/2012
1Nausea
08/2012
1Heart Failure
08/2012
1Eye Hemorrhage
08/2012
1Breast Neoplasms (Breast Cancer)
10/2010

Drug/Important Bio-Agent (IBA)

13afliberceptIBA
01/2022 - 08/2012
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2017 - 08/2012
3sagopiloneIBA
06/2013 - 10/2010
3Epothilones (Epothilone)IBA
06/2013 - 10/2010
2Retinaldehyde (Retinal)IBA
01/2019 - 08/2012
2Pharmaceutical PreparationsIBA
01/2019 - 12/2015
2Levonorgestrel (Plan B)FDA LinkGeneric
05/2015 - 05/2013
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2020
1regorafenibIBA
01/2019
1Ophthalmic Solutions (Eye Drops)IBA
01/2019
1ErbB Receptors (EGF Receptor)IBA
12/2015
1Circulating Tumor DNAIBA
12/2015
1Sorafenib (BAY 43-9006)FDA Link
12/2015
1Contraceptive Agents (Contraceptives)IBA
05/2015
1Tranexamic Acid (AMCA)FDA Link
05/2013
1Mefenamic Acid (Pontal)FDA Link
05/2013
1Acetylcarnitine (Alcar)IBA
01/2013
1PlatinumIBA
10/2010

Therapy/Procedure

5Lasers (Laser)
02/2017 - 08/2012
4Light Coagulation
02/2017 - 08/2012
2Therapeutics
02/2017 - 06/2013
1Photochemotherapy (Photodynamic Therapy)
05/2021
1Castration
01/2013
1Drug Therapy (Chemotherapy)
10/2010